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GASTROINTESTINAL INFECTIONS PART 2 - Coggle Diagram
GASTROINTESTINAL INFECTIONS PART 2
BACTERIA THAT INVADE THE CELLS OF THE GUT
3 common genera
Salmonella spp
Shigella spp
Yersinia spp
CLASSIFICATION OF SALMONELLA
two species
S. bongori
S. enterica
has 6 subspecies
has serovars; share common O and H antigens
Salmonella enterica serovar Typhi
cause typhoid fever
do not cause diarrhoea
can persist in gall bladder
Salmonella enterica serovar Enteritidis
Salmonella enterica serovar Minnesota
TRANSMISSION OF SALMONELLA
predominantly in foodborne pathogen
red and white meat
raw eggs
milk
person to person spread
contact with infected animals
SALMONELLA ENTERICA AND DISEASE
gram negative rod
need high dose to cause infection
bacteria adhere to epithelial cells of small intestine
host cell ruffles and bacteria become internalised
bacteria found in endocytic vacuole
vacuole migrates through cell
fuses with membrane
releases bacteria into sub epithelial tissues
get inflammatory response
evidence of toxin involvement
CLASSES OF DIARRHOEA-CAUSING E. COLI