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DIARRHEA, Ingestion of contaminated feed - Coggle Diagram
DIARRHEA
Loss of fluid
Reduction of fluid component in blood
lack of fluid lead to Increase blood viscosity and reduce blood flow
clotting factor in blood in contact and lead to intravascular clotting
thrombosis
thromboembolism
emboli lodge into a small terminal blood vessel in brain
blood flow into brain become obstructed
brain tissue will deprive of oxygen and nutrient, and metabolic waste accumulated
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decrease blood volume
(hypovolemia)
increase peripheral blood flow resistance
shunting of blood to vital organ
further decrease of blood volume, lead to hypoperfusion to vital organ
vital organ such as brain, heart, lung will not receive sufficient blood flow
multiple vital organ failure
peripheral tissue hypoperfusion
Loss of protein
Lack of protein in blood
(hypoproteinemia)
decrease oncotic pressure
in blood
Fluid move out from blood vessel into interstitial space
Accumulation of fluid
in the interstitial space
At lung, fluid accumulates
into alveolar lumen
Pulmonary edema
prevent gas exchange
respiratory failure
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Generalized edema
Ingestion of contaminated feed
Pathogen enter the mouth and pass through the esophagus into the stomach
Stomach contains HCl which can denature some bacteria
Some virulent bacteria can survive and enter the intestines
May infect duodenum, jejunum or ileum
Injure enterocytes
Trigger inflammatory response
Enteritis
Necrosis and sloughing off of enterocytes
Failure of crypt cells to replace the sloughed portion of enterocytes in time
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