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CV 2: Cardiac Cell Electrophysiology - Coggle Diagram
CV 2: Cardiac Cell Electrophysiology
Atrium and Ventricles APs
Phase 0: Upstroke
Na Influx
Phase 1: Early repolarization
Na close
Transient outward K+
Phase 2: Plateau
L-type Ca channels
Delayed Rectifier K+ Channels
Rapidly activating
Slowly activating
Phase 3: Repolarisation
Inward Rectifying K+ Channels
Phase 4: Resting
Pumps
3Na: 2K pump
3Na:1Ca2+ pump
ATP-driven Ca2+ pump
SAN & AVN APs
Slow and small Upstroke
L-Type Ca 2+
No early repolarization
No transient K+ channels
No plateau
L-type Ca2+ are already closed
No resting potential
Diastolic depolarization
Hyperpolarization-activated inward current channels
Depolarization from Na-Ca exchanger
T-type Ca2+ channels
MP and APs (General)
ANS
Sympathetic
increase activity
Parasympathetic
Decrease activity via acetylcholine regulated K+ channels