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Epigenetics - Coggle Diagram
Epigenetics
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DNA Methylation
Addition of methyl group to cytosine, specific motifs - CpG islands
Methylation may inhibit binding of activators and also block activator binding by drawing methyl-CpG binding proteins to induce heterochromatin formation by recruiting HDAC
Histone Acetylation
Induced by histone acetyl transferases (HATs) is associated w/ gene transcription while histone hypoacetylation included by histone deacetylase (HDAC or SIRT proteins) activity is associated w/ gene splicing
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