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DIM MSK, Anatomical bone - Coggle Diagram

- - - - pathophysiology
        
        Incorrect Ca:P imbalance, hypocalcaemia, stimulate PTH, resorption of Ca from bone, oseteopaenia
      - Radiographic features
        
        thin cortices
        
        spinal curvature
        
        Osteopaenia
        
        folding/compression fractures
        
        bowing/malformation of long bone
    - - Pathophysiology
        
        Phosphate retension by the kidneys
        Hyperphosphataemia, reciprocal hypocalcamia, stimulate PTH release, Ca resorption from the bone
      - radiographic features
        
        Similar to NSHPTH, but more localised to the skull
        
        loss of lamina dura, "floating teeth"
    - - Pathophysiology
        
        Inadequate plasma levels of Vit d + diet deficient Ca and P
      - Radiographic changes
        
        Marked widening of physes
        
        Flaring of metaphyses with beaked margins
        
        Generalised osteopaenia
        
        Spinal curvature
  - - - SX: Large breed dogs GSD 9m-2yrs males>females
      - Rads
        
        Middle stage
        
        Roughened endosteum
        
        Coarse trabeculation
        
        Coalescing of medullary opacities
        
        Mild solid periosteal reaction (femur)
        
        Late stage
        
        thickened endosteum
        
        Caorse trabeculation
        
        Lucent (hallow) medullary cavity for many years
        
        Regressed periosteal reaction
        
        Resolution medullary opacitites
        
        early stage
        
        Smudging of tubercule
        
        beginning of nutrient foramen
        
        patchy increased opacitites, fingerprint like
    - - Sx
        
        Young (3-8months)
        
        Rapidly growing large breeds
        
        Weimeraners
        
        Great Danes
        
        Metaphyses of long bones esp distal radius and ulna
      - Radiographic signs
        
        1-2 weeks later: “Metaphyseal paracortical cuffing”
        
        Linear mineralised opacities/ periosteal reaction parallel to the cortices
        
        Separated by a radiolucent line
        
        3-4 weeks later
        
        Remodels
        
        Usually bilaterally symmetrical
        
        Very opaque metaphyseal region
        
        Can affect skull
        
        Collar fuses with cortex
        
        Physes normal
        
        Early stage
        
        Irregular radiolucent line in metaphyses of long bones
        DD: haematogenous osteomyelitis
- - - - agressive
      - Early metastasis to lungs
    - - Distal radius
      - Distal femur
      - Proxmial humerus
      - proximal tibia
    - - may be lytic
      - amorphus bone
      - endosteal scalloping