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Integumentary System - Coggle Diagram
Integumentary System
Layers of Epidermis
Stratum Corneum
pH gradient
Protects from friction and water loss
Stratum Spinosum
Makes D3
Langerhans cells
Stratum Granulosum
Filaggrin
Keratohyalin
Lamellar Granules
Stratum Basela
Mitotically active cuboidal cells (one layer)
Pre D3 made here
Nerve Cells/Receptors
Pacinian Corpuscles
Deep pressure/ Vibrations/ Course Touch
In hypodermis
Merkel cell
Mechanoreceptors for gentle touch
Found in stratum basale
Cancer of this cell is rare but aggressive
Associated with free nerve fibers
high/low temp, pain, itch
Ruffini
encapsulated
Stimulated by tension and torque
Krause End Bulb
encapsulated
low frequency vibrations
Wound Healing
Blood Clot
Platelets aggregate via a fibrin mesh and form plug
Blood vessels constrict
Inflammation
Chemokines and cytokines released
Blood vessels dilate
Macrophages and neutrophils come and clean out microbes
Epithelization
Stem cells in the baseal layer start to proliferate to replace the lost cells
Fibroplasia
Fibroblasts starts to produce collagen
Granulation tissue begins to form
Primary Skin Function
Sweat and Oil production
Sensory