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Lung Cancer - Coggle Diagram

- - - - Genetic mutation and affects protein synthesis
        
        Disrupts the cell cycle
        
        Carcinogenesis occurs
- - - - Surgery followed by adjuvant chemotherapy, then concurrent chemo-radiotherapy.
    - - Chemo-radiotherapy then surgery if tumors become resectable
  - - - Chemotherapy to improve survival and alleviating symptoms.
- - - - Abnormal immune reactions to normal tissues, causing DNA damage
        
        Successful cancer cells produce a variety of cytokines and chemokines that are chemoattractant for stromal cells that infiltrate the tumor.
        
        The stromal reaction promotes tumor progression, including new blood vessel growth, tumor cell proliferation and differentiation, suppression of immune rejection and tumor cell apoptosis, invasion, and commitment to metastasis.