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Immune System - Coggle Diagram
Immune System
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Receptors and Response
MHC (Major Histocompatibility Complex) class 1 - presents antigens to CD8 T (cytotoxic) cell receptors, cell death occurs with pathogen, on all nucleated cells of body
MHC class 2 - endocytic vesicles and low pH, presents CD4 T (helper) cell receptors; presented by Dendritic cell/ macrophages, B cells
Allows activation to kill bacteria and parasites
and/or
have B cells secrete extracellular bacteria/toxins
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IL-1, IL-6, TNF-alpha, INF-alpha, INF-beta: induce immune Reponses
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Diseases and Vaccines
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Live attenuated vaccines: Causes live pathogen to become non-pathogenic to build immunity against virus
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Cells and Tissues
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Macrophage- wound healing, phagocytic, APC
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Dendritic cell- APC, phagocytic
Autoimmunity
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Hashimoto's thyroiditis- autoimmune disease; autoantibodies and T helper 1cells made for thyroid antigens
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Innate and Adaptive
Functions: Recognize, effectors, regulation, and memory
Innate: response in minutes to hours, not specific, same response each time
Major components: barriers (physical; skin/ chemical; acid), phagocytes, Pattern recognition molecules
First defense
Adaptive: responds within days, specific, quicker response by each exposer, includes T and B cells, antigen specific receptors, and antibodies
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