My Heart Skipped a Beat

Finding of X-Ray on Arrhythmia Patients

What to Assess

Position of Heart: 1/3 to right 2/3 to left, apex pointing to left

Heart Size: <50% chest diametre, normal ventricle/atrium size

Aortic Knuckle: on the left

What can be shown on X-Ray for patients with Arrhythmias

Enlargemnt of Ventricles

Bilateral Plueral Effusion

Enlargment of Atriums

Connection Between Valvular Heart Disease and Arrhythmias

Problem with valve --> Stenosis/Regurgitation --> Blood doesn't flow normally to ventricles --> Irregular Heartbeat

Hemodynamic Affects of Arrhythmia

Tachycardia

Reduced Cardiac Output

Reduced Ejection Fraction

Reduced Stroke Volume

Increased Myocardial Oxygen Demand

Atrial Fibrillation

Reduced Ventricular filling by around 10% at rest

Reduced Ventricular filling by around 40% during exercise

Ventricular Fibrillation

Most Severe

Can cause 0 cardiac output

Digoxin Toxicity

Brain

Eyes

GIT

Heart

Lack of appetite

Vomitting

Nausea

Headache

Confusion

Anxiety

Blurred vision

Seeing halos around bright objects

Irregular heart beat

Palpitations

AV Block

Definition

interruption of electrical conduction from the atria to ventricle due to conduction system abnormalities.

Causes

Post cardiac operation

Hypertension medication

Age

Degrees

1st

Electrical Impulses are slow

2nd

Type1

atrial impulses is blocked in AV node and fails to conduct to the ventricle

Type 2

the episodic atrial impulses are blocked in the diseased AV node.

3rd

Atrial impulses are completely blocked from reaching the ventricles.

Epidemiology

In UK, atrial fibrillation affecting up to 5% people aged 75 or over.

In Qatar, there is significant high incidence of atrial fibrillation during 1993-1997, it might be attributed to the environmental factor and pollution.

ECG

Definition

A machine that records the electrical signals in the heart

Electrodes

Conductive pads that are attached to the skin

10 electrodes will be placed at specific spots on the patient

RL electrode used as a reference electrode

Leads

Electrical potential difference between two electrodes

12 Leads gives a view of the heart electrical activity from two planes frontal (limb) and horizontal (pericardial)

Frontal Plane

Unipolar vectors

Bipolar Leads

aVR, aVF and aVL

I, II and III

Horizontal Plane

They include: V1, V2, V3, V4, V5 and V6

Unipolar leads

Six leads give a view of the heart

Readings

Depolarization

Repolarization

Interpretation

Changes the membrane potential from negative to positive

Goes from the – pole to the + pole

Changes the membrane potential from positive to negative

Atrium: first cell to be depolarized is the first to be repolarized

Ventricles: first cell to be depolarized is the last to be repolarized

P wave: Atrial repolarization

QRS interval: ventricular depolarization

T wave: Ventricular repolarization

Atrial Fibrillation

Causes may be problem with the heart structure, Coronary heart arteries, Heart attack, CHD.

Accumulation of blood in the atrium may form blood clots

Uncoordinated electrical impulses suddenly start firing in the atria

The heartbeat is around >350 bpm

Atrial Flutter

Caused by problems in the heart conductive system

Increases the risk of stroke and heart failure

It’s a type of arrhythmia

The heartbeat is around 250-350 bpm

The atriums beat too quickly, this causes the heart to beat in a fast, but usually in a regular rhythm

Patients could be asymptomatic

Supraventricular Tachycardia

it’s as an irregularly fast or erratic heartbeat (arrhythmia) that affects the heart's upper chambers

The heart beats about 150 to 220 bpm

Prognosis

Factors Affecting AFib prognosis

Health Conditions

Medication

Gender

Treatment and lifestyle

Age

Pacemaker

Definition

a small device implanted in the chest to help control the heartbeat

How it works

: it contains a pulse generator and leads which send electrical signals to correct the beat when needed

Implantable cardioverter-defibrillator

small battery powered device placed in the chest to detect and stop arrhythmias by sending electric shocks

AI Application

Deep learning model

Cycle-GAN

uses the “deep neural network” algorithm to learn by itself how to interpret data by analyzing large amounts of data and coming up with its own interpretation patterns (can be used to identify PQRST waves and any abnormalities)

can be used to restore ECGs in order to better identify the electrical waves and find any abnormalities in the signal

Wearable Devices

Come in a variety of shapes and sizes like watches (apple watch, fitbit), rings (oura ring), bands (kardiaband), and patches

Most are used to monitor HR, pulse, rhythm, BP, body temp, sleep, fitness, weight and BMI, risk of falling

Conducting System in the heart

Signal Flows through contraction progress

  1. SA Node 2. AV Node 3. Bundle of HIS 4. Left/Right Bundle Branches 5. Purkinje Fibers

Cardiac action Potential

Phase 0

Rapid Na+influx through open fast Na+channels

Phase 1

Transient K+channels open and K+efflux begins to return the membrane potential to 0 mV

Phase 2

Influx of Ca2+through Ca2+ channels balances the K+efflux to create the plateau phase.

Phase 3

Ca2+ channels close and rectifier K+channels remain open to return the membrane potential to -90 mV

Phase 4

Na+and Ca2+channels are closed, while open K+rectifier channels maintain the negative resting potential

Heart Arrhythmia

Definition

A heart arrhythmia is an irregular heartbeat. Heart rhythm problems (heart arrhythmias) occur when the electrical signals that coordinate the heart's beats don't work properly.

Types

Atrial flatter

Ventricular tachycardia

Atrial fibrillation

Ventricular fibrillation

Relationship between cardiac arrest and arrhythmias

Can happen when

Heart beats dangerously fast.

Ventricles may flutter or quiver (ventricular fibrillation).

Heart’s electrical system malfunctions and suddenly becomes irregular.

Pharmacological Treatment of Arrhythmias

Vaughan-Williams Calssification

Class III

Class IV

Class II

Class V

Class I

Voltage gated Na+ channel blockers

B-adrenergix receptor blockers

Voltage gated K+ channel blockers

Voltage gated Ca2+ channel blockers

Various