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Endocrine Disorders - Coggle Diagram
Endocrine Disorders
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Causes
Trauma, ischemia, and infarction can cause sudden loss of pituitary function (Sheehan’s syndrome)
Primary adenoma
- Most common cause
- Benign neoplasm
- With growth can compress pituitary gland in sella turcica (Interfere with pituitary function)
Pituitary tumor, brain surgery, radiation of brain tumor, congenital disorder
Craniopharyngioma
- Benign neoplasm close to pituitary gland or pituitary stalk
Pituitary apoplexy
- Sudden destruction of the pituitary tissue due to infarction or hemorrhage into gland
- Traumatic brain injury most common cause
Sheehan’s Syndrome
- Ischemia or infarction of the pituitary after childbirth because of severe hemorrhage
- Degree of necrosis correlates with hemorrhage
- Develop deficiency of ACTH, TSH, FSH, LH, ADH, and PRL
Diabetes Insipidus (DI)
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Dilute, large volume urine
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Causes
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Endocrine-disrupting compounds (EDC)- Chemical in environment that can alter endogenous hormone functions
Autoimmune - Antibodies target endocrine gland, may cause hypofunction or hyperfunction
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Hypopituitarism
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Panhypopituitarism
- Complete loss of all pituitary hormones
- Rare
Hyperpituitarism
Pituitary adenoma
- Most common cause
- May produce ACTH, TSH, or GH
- Prolactinoma most common form: secretes PRL
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