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Cell Division - Coggle Diagram
Cell Division
Stem cells
Function
The inner cells of embryos are embryonic stem cells that can differentiate to form all of the specialised cells in your body.
When you're an adult, some stem cells remain. An adult stem cell is an undifferentiated cell that can give rise to many more cells of the same type.
A good source is bone marrow. Scientists now think there may be a small number of stem cells in most different tissue; eg. brain, liver, blood and muscle.
Some differentiated cells cannot divide to replace themselves and so stem cells start dividing in their place to replace the damaged cells.
Uses
Many people suffer and die because parts of their body stop working. EG. spinal injuries can cause paralysis, type 1 diabetes caused by specialised cells in the pancreas stop working.
Therefore, stem cells can be cultured to form any type of cell that is needed. As a result, people with life threatening injuries or diseases can be treated.
In 1998, the first breakthrough happened. Two scientists managed to culture embryonic stem cells.
In 2010, the first trials for injecting nerve cells grown from stem cells into the spinal cord of paralysed patients were carried out.
In 2014, doctors transplanted embryonic stem cells into the eyes of people going blind as a result of mascular degeneration -> all of the patients found they could see better.
Scientists are using different types of stem cells to try and grow cells that are sensitive to blood sugar levels and produce insulin to help people with diabetes.
In Plants
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Used in agriculture to produce large numbers of identical crops with special features, eg. disease resistance
Problems
Embryonic stem cells
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Some people question whether it's ethically moral; feel that as the embryo cannot give permission, using it is a violation against its human rights.
Religious beliefs of others mean they cannot accept any interference with the process of human reproduction.
Progress has been very slow, difficult, expensive and hard to control. However, signals that control differentiation are still not fully understood.
Divide very quickly, which is why they're so useful. But there's concern that they could cause cancer if they are used to treat people.
Adult stem cells
Risk they may be infected with viruses and so could transfer infection onto the already ill patient.
If adult stem cells are used from someone unrelated they could be rejected and cause an autoimmune response.
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Many people feel that too much money and research is being put into stem cells that could be used for other areas of medicine.
Future
Scientists have found stem cells in the umbilical cord of newborn babies and the amniotic fluid that surrounds the fetus.
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Therapeutic cloning
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Stem cells made to differentiate into different tissues (EG. spinal cord, heart, kidney, insulin producing cells)
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Scientists have found stem cells in the tubes connecting the liver and pancreas to the small intestine which can be turned into insulin producing cells.
In the UK, stem cell research is being carried out into potential therapies:
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Cell division
Cells are needed for an organism to grow and therefore need to be replaced. These new cells need to have the exact same genetic information to do the same job.
Cell information
Chromosomes are found in the nucleus of the cell and carry the genes that contain the instructions for making new cells and all the tissues and organs in the body.
A gene is a section of DNA that has a small bit of information that controls a characteristic or part of a characteristic of the body.
Genes are grouped together on chromosomes; a chromosome may carry hundreds or even thousands of genes.
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Cell cycle
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Stage 2 (MITOSIS) - one set of each chromosome is pulled to each end of the dividing cell and the nucleus divides.
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Stage 1 - longest stage in the cycle. Replication of DNA to form 2 copies of each chromosome and synthesis of sub-cellular structures (mitochondria, ribosomes and chloroplasts) ready for the cell to divide
Cell division by mitosis produces the additional cells needed for growth and development in multicellular organisms and for the replacement of damaged cells.
As you get older, mitosis slows down and you start to show the signs of ageing (eg. wrinkles)
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