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ANTIBIOTICS - Coggle Diagram
ANTIBIOTICS
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- bacteriostatic = inhibit bacterial growth
- bactericidal = kill the bacterium
- bacteriolytic = lysis of the bacterium
spectrum of action:
- broad, e.g. tetracycline
- narrow, e.g. against mycobacteria
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RESISTANCE MECHANISMS: - production of enzymes inactivating the drug - modification of the drug's target - decreased permeability to the drug - development of an alternative metabolic pathway to that inhibited by the drug
drugs targeting mycobacteria:
- ethambutol (inhibits arabinogalactan synthesis)
- isoniazid (inhibits mycolic acid synthesis)