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SEIZURE - Coggle Diagram
SEIZURE
Unprovoked recurrent (epileptic)
Focal
Manifestations arising from one portion of the brain, especially temporal lobe
Focal unaware (complex partial)
May have post-ictal drowsiness, confusion
Generally last 1-2 minutes
Aura + become unaware of surroundings: may have memory loss, automatisms (lip smacking, fumbling, wandering)
Focal aware (simple partial)
Aura without altered awareness
i.e. abnormal motor, sensory, autonomic or psychic experience
Todd's paralysis (weakness of limbs) may follow
May progress to secondary generalised
Generalised
Bisynchronous epileptiform activity in both cerebral hemispheres; originate in midbrain/ brainstem
Convulsive
Tonic clonic (grand mal)
Aura / loss of consciousness and phasic tonic stiffening of limbs (10-60s) followed by repetitive clonic jerking (s-mins)
Tonic: rigidity, epileptic cry, tongue biting, incontinence, hypoxia/ cyanosis
Clonic: convulsions, eye-rolling, tachycardia, difficulty breathing
Post-ictal drowsiness, confusion, headache
Myoclonic
Brief, shock-like jerking of muscles where patient remains aware. Often affects upper limbs and worse in morning: spill drink, drop toothbrush
May progress to tonic-clonic
Tonic
Greatly increased tone across the whole body; often fall
Clonic
Rapid alternating contraction and relaxation of muscle
Non-convulsive
Atonic
Sudden brief loss of muscle tone
Absence (petitie mal)
Abrupt cessation of activity and responsiveness lasting 5-15s
Minimal associated movements, no aura or post-ictal state
Associated with cognitive impairment but tend to resolve by adulthood
Criteria: at least 2 unprovoked seizures more than 24 hours apart OR one unprovoked seizure and a probability of further seizures >60%
Pharmacotherapy
Carbamazepine (Na+ channel blocker): first line focal
Lamotrigine (Na+ channel blocker): focal or generalised
Phenytoin (Na+ channel blocker): focal or convulsive
Ethosuximide (Ca+2 channel inhibitor): absence
Sodium valproate (increase GABA): absence, generalised
Triggers:physical/ emotional stress, intoxication, sleep deprivation
Provoked recurrent (non-epileptic/ organic secondary
Conditions irritating the brain
Metabolic
Hypo/hyperglycaemia, low Na+/ Ca+2, uraemia
Structural
Congenital, neoplasm, trauma
Febrile
Infection
Sepsis, encephalitis, meningitis
Degenerative
Hypoxia
AF, respiratory depression
Vascular
Intracerebral haemorrhage, SAH, SDH, stoke
Psychogenic/ pseudo
Certain mental illnesses can cause symptoms that resemble seizure