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Oxidative Pentose Phosphate Pathway - Coggle Diagram
Oxidative Pentose Phosphate Pathway
Functions:
glucose oxidation
production of NADPH rather than NADH
NADPH used for cytosolic biosynthesis
NADH may be oxidized by MET
Formation:
2e- transferred from organic compound to NADP+
Electrons used to reduce other organic compounds or transferred to MET
Generates C3 photosynthetic intermediates before developing leaf is fully autotrophic
generates ribose-5-P for biosynthesis
generates Erythrose-4-P for synthesis
Location:
cytoplasm
chloroplast in dark
Substrates:
Glc-6-P from glycolysis
Glyceraldehyde-3-P from glycolysis
Glucose is partitioned between glycolysis and oxidative pentose phosphate pathways to balance biosynthetic and energy needs
FAMILIARIZE WITH P4
OPPP Regulation
Cytoplasmic OPPP Regulation
Glc-6-P Dehydrogenase sensitive to NADPH/NADP ratio, with increased NADPH/NADP leading to decreased G6PDH activity
Chloroplastic OPPP Regulation
possibly functions in dark
unlikely to function in light
Glc-6-P dehydrogenase
Sensitive to NADPH/NADP ratio, with greater NADPH/NADP leading to decreased activity
inhibited by thioredoxin system
impacted by mass action of C3 PS intermediates