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INFECTIOUS DISEASES 4 - Coggle Diagram
INFECTIOUS DISEASES 4
VIROLOGY
Epstein-Barr (EBV)
- sốt/ viêm hầu họng+ hạch
- +/-gan lach to+ mệt mỏi (Jaundice/Hepatitis)
CLS
- Anti-heterophile antibodie (Monospot test)-negative initially
in 1st week
- tăng bạch cầu đon nhân(MONONUCLEOSIS)
- +/ - viêm gan
- avoid contact sport> 3 W--->splenic rupture
- Autoimmune hemolytic anemia and thrombocytopenia
RUBELLA
LS
- bẩm sinh: Điếc, PDA, đục thủy tinh thể
- trẻ em : so62t/ viêm kết mạc ko xuất tiết+ hồng ban
- lớn: giồng trẻ+viêm khớp
CLS
- PCR
- IgM nhiêm/IgG dã
bc:
- post-infectious encephalitis
- 1st trimester are at ↑ risk of miscarriage
Maculopapular erythematous rash:
- từ trên xuống dưới - đối xứng
- cuoi cung tay chân (cò thể)
VARICELLA ZOSTER
Post-exposure prophylaxis
- history of immunity ( prior infection or vaccination)
- yes: theo dõi
- no:
- HIV:VZIG within 10 day
- No HIV: Vaccine
- Vaccine is live attenuated and in CI in pregnancy and immunocompromised
- VZIG may not prevent infection but ↓ severity
-
HSV ENCEPHALITIS
- sốt/lơ mơ/co giật
- hyperreflexia
- dich NT : BTh+ PCR
-
RISK FACTORS FOR NEONATAL HSV INFECTION
- Mẹ HSV
- vỡ ói kéo dài>18h
- Sinh ngã am đạo+ đã có san thương
- sinh non
-
-
CHIKUNGUNYA FEVER
- South America/tropical/south asian
- Ades mosquito ( same as Dengue fever)
- sốt/ polyarthralgias
- viem kết mac/ maculapapula rash
CLS
- giam lympho,giảm tiểu cầu, tăng men gan
MEASLES
Rash similar to rubella but more gradual spread and appears darker (reddish brown)
LS
- conjunctivitis/ coryza/cough/Koplik spots
- ban sâm màu hơn/lan theo chiểu dọc/ bụng di ra/ luôn luôn có tay chân
CLS
- PCR
- IgM/IgG
-
HEPATITIS B
- cấp: HbsAg/HBeAg/HBV DNA: tắng cung lúc vs TC
- mạn:HbsAg/HBeAg/HBV DNA: tăng kéo dài> 6 tháng
HEPATITIS B AND FULMINANT HEPATIC FAILURE
90 B recover/0.1-0.5% FHF
- Fulminant hepatic failure:- hepatic encephalopathy after onset of acute liver failure.
- Risk factors for FHF :acetaminophen, alcohol, methamphetamine và B D coinfected
-
CCD:
- irreversible cardiopulmonary disease
- <5years) malignancy external to liver
- active alcohol or drug
abuse.
dtri
các đối tượng cần diều trị
- acute liver failure
- clinical complications of cirrhhosis
- Cirrhosis +HBV DNA
- No cirrhosis + HBeAg +,HBV DNA>20.000, ALT> x2
- prevent HBV reaction during chemotherapy /immunosuppression
entercair/tenofovir: dung thời gian dài + xơ gan mất bù
interferon: ngăn+ ko dùng cho BN xxo7 gan ma61t bù
- gd sớm:
HbsAg/HBeAg/HBV DNA + anti HBc IgM
- window phase:
anti HBc IgM+HBV DNA chuẩn bị cấp)
- Recovvery phase:
anti HBc IgG +Anti HBs + Anti HBe
- chronic HBV carrier:
HbsAg+anti HBc IgG
- actue/ chronic
HbsAg/HBeAg/HBV DNA + anti HBc IgM +anti HBc IgG
- Vaccinsted
Anti HBs
- immune due to natural HBV infection
anti HBc IgG +Anti HBs
-
HEPATITIS C
-: exposure to contaminated blood
chronic LS
- Asymptomatic / develop fatigue
- nonspecific symptoms
CLS
- transaminases ( tăng or binh thường)
- Anti HCV IgM
biểu hiện ngoài gan:
- heme : cryoglobulinemia ( tồn thương da/ khớp ,tk)
- renal : viêm càu than tằng sinh màng
- skin:Porphyria cutanea tarda
- endocrine: tăng nguy co DTD
fragile skin, photosensitivity, vesicles and erosions on dorsum of hand
HEPATITIS C IN PREGNANCY
- BC: DTD thai kỳ/ sinh non/ ứ mật
- DTri: ko nên dùng RIbavirin (quái thai)/ hepatitis A,B vaccnated
- ngăn ngừa: đánh giá viral load me/ nên cho con bú nếu....
-
RABIES
Encephalitic
- hydrophobia
- Aerophobia
- pharygneal spasm,spastic paralyis
- Agitation
Paralytic
- faccid paralytic
- immune globuline + Vaccine immediately
BC: coma,RSD/death within weeks
-
-
HEPATITIS A:
- viêm gan cấp
- anti HAV IgM/igG
- Close contacts should promptly be given immune globulin
- travelling to endemic areas/sex with men--> vaccine