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Vibrio Cholerae, Pathogenesis, Pathogenicity, Members name: Abigail…
Vibrio Cholerae
Pathogenecity
Pathogenesis
caused by toxigenic Vibrio cholerae
depends on the synergistic effect of a number of factors produced by toxigenic V. cholerae.
stomach
small intestine
multiplies in intestinal mucosa
produce cholera toxin
the toxin bind with plasma membrane of intestinal epithelial cell
release an enzymatically active subunit
cAMP production
high intracellular cAMP level blocks absorption of sodium and chloride by the microvilli
promotes the secretion of chloride, bicarbonate, potassium and water
1 more item...
Pathogenicity
motile bacterium
Members name:
Abigail Priyanka Thomas
Roshini A/P R Asogan
Priya Darshini A/P Subramaniam