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Patient Involvement - Coggle Diagram
Patient Involvement
Possible Repeated Event
High Effort/Time
Invasive
Subdermal electrodes on head/neck
Electrode snake via ear-tube
Non-Invasive
Seizure induction to check anxiety
Flashing lights
CO2/ O2 deprivation
Vagus nerve stimulation
Seizure room
Neuromodulation
Microwaves
Ultrasound
Electrical
Low Effort/Time
Expanded neurological/physical exams
Psych test that can distinguish causes of anxiety
Drugs
Upregulation/downregulation of gene targets
Reduce blood-flow to seizing structures
Raise seizure threshold of deep structures
Adjust CO2 level in blood
Plasmid with electric induced promoter and anti-anxiety effector
Seizure colored poop
Swallow device that travels to electrical activity
Medium Effort/Time
Standard EEG w/ modifications
Increase resolution
Creative Electrode placement
Ear EEG (like hearing aid)
Mouth EEG on retainer
Long-Term Wearable Monitoring Suite
Nasopharyngeal electrodes
Roof-of-Mouth Electrodes
Temporal EEG
Outer ear electrodes
VR to induce anxiety
Blood test during anxiety attack
Non-EEG tests
Integrated Alternative Monitoring Helmet
fNIRS
Machine-learning integration
SPECT to measure blood flow
Integrated electrodes
Ingestible liquid magnet to induce measurable field
Full-Body IR scan for temperature changes
Dry context temporal recordings
Track skin flushing during anxiety
SPECT
Comorbidities/non-neuron indicators
O2 sensor to detect brain acidity
Measure hormones in brain from blood taken during anxiety
Likely Singular Event, or None
Noninvasive
Fast acting anti-epilepsy drug as anxiety treatment
Blood required
IPSC single-cell screening behavior
Cell-level
System-level
Colored by seizure
Show specific characteristics of anxiety
IPSC-based organoid growth
Whole Organoid screening
Penicillin tests
Benadryl tests
pH tests
Organoid slice screening (microfluidic chip)
Penicillin tests
Benadryl tests
pH tests
Ablate deep structures
Microwaves
Ultrasound
Post-seizure hair test for anxiety markers
Brain connectivity analysis to find proxies for deep structures
Non-Invasive vagus nerve stimulator
Invasive
Ablate deep structures
Snake wire
Implantation of vagus nerve stimulator
Unsure
Hijack gut/brain interface
Gut expression of anti-epileptic gene