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Non Neoplasia Group 6, Peripheral: Gingival or alveolar soft tissue,…

- - - - Occurs more often in maxilla than mandible
      - More common in children/young adults, either sex
      - Involves only a single bone
      - Clinical exam shows a painless swelling of buccal plate
    - - When long bones are involved, may exhibit bowing and a dull pain
      - May have light brown skin lesions (macules called cafe au lait spots)
      - Occurs mostly in children, especially females
      - Typically a painless, progressive, unilateral enlargement of maxilla or mandible
      - Involves more than one bone
      - Radiographic appearance: a diffuse radiopacity like ground glass
- - - - Clinical Signs & Symptoms
        
        ✦ Skull: Severe headaches, dizziness, deafness
        ✦ Pain (enlarging bone puts pressure n cranial nerves)
    - - Clinical Signs & Symptoms
        
        ✦ Spacing between teeth as bone enlarges
        ✦ Edentulous patients complain denture no longer fit
        ✦Pain
      - Radiographic Appearance
        
        ✦ Early stages: Not specific
        ✦ Later stages: Patchy, radiolucency & radiopacity referred to as "cotton wool"
        ✦ Hypercementosis, loss of lamina dura, & obliteration of PDL
  - - - Laboratory Testing
        ✦ Serum alkaline phosphate level is elevated
        Bodansky Units Normal=1.5-5 > Can be as high as 250!
        King-Armstrong Units Normal=5-10 > Can be as high as 200+!
        ✦ Serum, calcium & phosphorus levels are normal
      - Microscopic
        ✦ Bone trabeculae surfaced by many osteoblasts & osteoclasts
        ✦ Mosaic bone from prominent reversal lines as a result of resorption and deposition
        ✦ Connective tissue is high vascularized (overlying skin may feel warm!)
- - - - Peripheral locations are more frequent in people between 30-45 years old and more common in females than males