Please enable JavaScript.
Coggle requires JavaScript to display documents.
Non Neoplastic Diseases of Bone :Molly and Hector - Coggle Diagram
Non Neoplastic Diseases of Bone :
Molly and Hector
Benign Fibro-Osseous Lesions
Focal Cemento-Osseous Dysplasia
Asymptomatic fibro-osseous lesion that shares similar microscopic features with periapical cemento-osseous dysplasia and florid cemento-osseous dysplasia
● Unique clinical and radiographic features
● Arises in posterior mandibleisolated, well-delineated, less than 1.5 cm
● Prognosis= Excellent
Florid Cemento-Osseous Dysplasia
● Involves multiple quadrants maxilla/mandible
● Often in posterior
● Radiopaque masses of irregular opacification: no bone expansion
● Asymptomatic
Fibrous Dysplasia
2 Types:
Polystotic
o Involves more than 1 bone (skull, clavicle, long bone)
o Asymptomatic
o Long bones may exhibit Pain, Bowing, Pathologic fractures
o Skin lesions (light brown macules=café au lait)
o 3 types: Craniofacial, Jaffe, Albright syndrome
Monostotic
o Most common type- 85%
o Involves single bone (ribs, femur, tibia)
o In maxilla and extends to maxillary sinuses and surrounding bones (Craniofacial fibrous dysplasia
● Replacement of bone w/ abnormal fibrous connective tissue interspersed w/ varying amts of calcified material
● Underlying cause: genetic mutation
● Earlier the genetic mutation occurs=more severe
● Painless, progressive
Periapical Cemento-Osseous Dysplasia
● Affects periapical bone
● Bone in apical area of multiple teeth may be involved
● Affects VITAL TEETH
● Composed of fibrous tissue and calcifications
● Remains asymptomatic & localized
Central Giant Cell Granuloma
● Intraosseous lesion of unclear pathogenesis
● Within gingival or alveolar soft tissue
● Uncommon in ramus
● Slow growing & destructive
● Discomfort, NO pain
● 2 types:
○ Non-aggressive -Small, asymptomatic, does not cause root resorption or cortical perforation
○ Aggressive- Large, painful, destructive, causes root resorption and cortical perforation
● May recur
● Cause: UNKNOWN
Paget Disease of Bone
● Chronic metabolic bone disease
● Characterized by: abnormal bone metabolism= resorption, osteoblastic repair, and remineralization
● Jaw=Painful
● Other bones= severe headache, dizziness, deafness (due to enlarging bone pressure on cranial nerves)
● Hypercementosis, loss of lamina dura, obliteration of PDL may occur
● Slowly progressive
● Complications: fractures of involved bone, development of malignant tumors (osteosarcoma)
● Cause: Chronic metabolic bone disease; Cause unknown
Osteomalacia
● Develops over long period of time
● Calcium deficiency
● May be induced by certain tumors
● Bones susceptible to fractures
● Cause: Long term: deficiency of calcium Children: Nutritional deficiency of Vitamin D Adults: Malabsorption syndromes, drugs, liver disease, kidney disease, chronic use of antacids
