Please enable JavaScript.

Coggle requires JavaScript to display documents.

Clinical Day 10/5/21 - Coggle Diagram

- - - - activate alveolar macrophages and recruit neutrophils to the lungs,
        
        release leukotrienes, oxidants, platelet-activating factor, and proteases.
        
        damage capillary endothelium and alveolar epithelium, disrupting the barriers between capillaries and airspaces
        
        Edema fluid, protein, and cellular debris flood the airspaces and interstitium
        
        disruption of surfactant, airspace collapse, ventilation-perfusion mismatch, shunting, and pulmonary hypertension
- - - - Deceased Cardiac output to body
        
        Blood back up into Left atrium
        
        Pulmonary congestion, dyspnea, activity intolerance
        
        Pulmonary edema and right sided heart failure
  - - - dysrhythmias
      - cardiomyopathies: HTN, CAD, Substance Abuse
      - MI
      - Congitiatl defects
      - cardiac rhythm changes
- - - - collects in alveolar
        
        impaired gas exhange
- - - - destruction of cells by viral attack or host immune response, as well as the increase in cytokines leads to infiltration of proteinaceous fluids into the lung
        
        Antibodies to SARS-CoV-2 created humoral immune response
      - vascular endothelium expresses ACE2, direct viral damage to these cells leads to hypercoagulable profile of COVID-19 through the intrinsic pathway of the coagulation cascade.
    - - Fever
      - cough
      - dyspnea
      - headache
      - fatigue
      - myalgias
      - new smell and taste disorder
      - nausea, vomiting, diarrhea
      - Dermatitis, rash, petacheia (bc of bleeding)
  - - - Antiphyretics
      - anticoagulants
      - pulmonary vasodialors
      - glucocorticoids
      - antiviral
      - antimaleraia
      - convalescent plasma
      - interleukin-6