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Portal Hypertension
Resistance to portal flow and increased portal venous…
Portal Hypertension
Resistance to portal flow and increased portal venous inflow
Caused by increased resistance to blood flow through the liver and increased blood flow d/t vasodilation
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Transjugular Intrahepatic Portosystemic Shunt
-Stent placed between portal circulation and hepatic vein
-Decreases Na retention
-Improves renal response to diuretic therapy
-Prevents recurrence of fluid accumulation
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Cirrhosis
Complications
Portal HTN
Persistent increase in pressure within portal vein, see ascites, esophageal varicies, prominent abd veins
Ascites
-Accumulation of free fluid containing almost pure plasma in peritoneal cavity.
-Sodium and water retention
Bleeding esophageal varices
-Fragile, thin walled esophageal veins become distended or irritated and rupture-loose lots of blood
-Tx: BB
Coagulation defects
Blood doesn't clot bc of decrease synthesis of bile fat in liver which prevents absorption of fat soluble vitamins (vitamin K)
Hepatorenal syndrome
Sudden increase in urinary flow, elevated BUN and Cr with abnormally decrease urine sodium excretion and increase urine osmolarity
Portal-systemic encephalopathy
-Seen in ESRD and cirrhosis
-Altered LOC, impaired thinking process, neuromuscular disturbances
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Facts
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Types
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Billiary
biliary obstruction, bile stasis, inflammation, diffuse hepatic fibrosis, PBC, PSC
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Interventions
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Liver transplant
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Selection of a patient for liver transplantation is a multidisciplinary process that requires a complete assessment
-Scoring used to see how high they are on the transplant list
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