PCT reabsorption - into vasa recta
Na+, Cl-, K+, glucose, amino acid, urea, bicarbonate, Ca2+ water
Pump involved:
Na+/H+ pump - Na+ reabsorb into cell of PCT then use Na+/K+/ATPase pump , Na+ reabsorb into vasa recta
Facilitated transport - Na+, glucose, a.a
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PCT secretion
creatinine, some drugs, H+(acidic)
PCT regulate acid-base balance
When H+ secreted into PCT, H+ reacts with HCO3- = carbonic acid, H2CO3 with carbonic hydrase enzyme
H2CO3 can be converted into H2O and CO2 ( both diffused into cell and into circulation for CO2)
H+ reabsorbed into PCT cell from lumen PCT and from circulation secretion can go thru H2CO3 process again with CO2 and so on - regulate
HCO3- can be reabsorbed into circulation thru Na+-dependent pump - to increase blood pH, more alkali
When CO2 increase, it gets acidic as H+ increase