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PANNICULITIS - Coggle Diagram
PANNICULITIS
SUMMARY OF APPROACH
1) Location of the most intense inflammatory infiltrate: septal or lobular
2) Presence or absence of vasculitis
3) Size of blood vessel involved by vasculitis
4) Nature of inflammatory cell infiltrate
5) Type of fat necrosis
6) Special stains/IHC/gene rearrangement studies
DEFINITION
- Panniculitides: a group of diseases characterized by an inflammatory process that originates primarily in the subcutaneous tissue (panniculus adiposus = subcutaneous fatty tissue)
- This term includes a heterogeneous group of disorders that can result from an inflammatory or immunological response associated with infectious, rheumatological, enzymatic or autoinflammatory/autoimmune disease
- Classified into septal or lobular types
TYPES
-
LOBULAR
-
WITHOUT VASCULITIS
LOBULAR PANNICULITIDES, MOSTLY LYMPHOCYTIC
LOBULAR PANNICULITIDES, MOSTLY HISTIOCYTIC
LOBULAR PANNICULITIDES, MOSTLY NEUTROPHILIC
LOBULAR PANNICULITIDES, MOSTLY EOSINOPHILIC
LOBULAR PANNICULITIDES, WITH SCARCE INFLAMMATION