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Types of Hormonal and Metabolic Dysfunction - Coggle Diagram
Types of Hormonal and Metabolic Dysfunction
Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH)
Clinical Manifestations
Anorexia, Nausea, vomiting, headache,
Irritability, disorientation, muscle cramps, weakness
Decreased, concentrated urine output
Treatment
Removal of DIADH
Water Restriction
Hypertonic intravenous (IV) Solutions
Diagnostic Criteria
Hyponatremia
Hypertonicity
Decreased urine volume
Highly concentrated urine with high sodium volume
Absence of renal, adrenal, or thyroid abnormalities
Diabetes Insipidus
Diagnostic Criteria
Urine specific gravity of 1.005 or less and a urine osmolality less than 200 mOsm/kg
Physical exam: dehydration and enlargement of bladder
Laboratory measures: Serum solute concertation, ADH levels, urine-specific gravity
Treatment
Hydration
Pharmacologic treatment, Desmopressin
Clinical Manifestations
Excessive thirst
Polyuria (Large Volume urine output)
Hyperosmolality, severe dehydration
Hyperthyroidism
Clinical Manifestations
Gorier
Exophthalmos
Weight loss, agitation, restlessness, sweating, heat intolerance diarrhea, tachycardia, palpations, tremors, fine hair, oily skin, irregular menstruations
Treatment
Ablation of the thyroid gland
Medications that block thyroid hormone production
Diagnostic Criteria
Physical exam: enlarged thyroid gland, protrusion of eyes
TSH levels
Serum-Free thyroxine measurement
Hypothyroidism
Clinical manifestations
Fatigue, weakness, cold intolerance, weight gain
Dry skin, course hair, constipation, lethargy, impaired reproduction's, impaired memory
Myxedema
Treatment
Levothyroxine
Lifelong thyroid hormone therapy
Diagnostic criteria
Testing labs for TSH, T4, T3 levels
Antithyroglobulin test
Thyroid autoantibodies
Cushing Syndrome
Treatment
Corticosteroid medication
Surgery, Radiation
Diagnostic Criteria
24 hour urine Collection (Elevated Cortisol)
Imaging studies
Clinical Manifestations
Striae, weakness, muscle wasting,
Obesity of the trunk, face, and upper back
"Moon face" "Buffalo hump"
Atrophic, thin skin
Addison Disease
Clinical Manifestations
Hyperpigmentation in skin and mucous membranes :
Treatment
Oral replacement of glucocorticoid mineralocorticoid hormones
Isotonic IV fluid replacement
Diagnostic Criteria
Depressed corticosteroid levels after ACTH
Electrolyte levels (Hyponatremia and hyperkalemia)