Bone and muscle deterioration

Without gravity effects

Skeletal muscle not required to maintain posture

Muscle groups differs moving in weightless environment than in terrestrial

No weight on back or leg muscle

Weakens over time and gets smaller

With no regular exercise

Astronauts loses 20% of their muscle mass in 5-11 days

Muscle fibres also changes

Slow-twitch endurance fibres that maintain posture are replaced by fast-twitch rapidly contracting fibres(insufficient for any heavy labour)

Bone metabolism also changes

In microgravity there is very little mechanical stress

Results in loss of bones tissue
1.5% per month

Hip

Femur

From lower vertebrae

Decreases load on bones

Makes bones frail

Resulting in symptoms resembling osteoporosis

Increases osteoclast activity due to microgravity

Osteoclast: breaks bones into minerals that are absorbed by body

Osteoblast are not consecutively active so causes bones to demenished without recovery

Particularly seen in pelvic region

As this region Carrie's biggest lead with gravity present