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Alzheimer's, NEUROLOGICAL DISORDERES - Coggle Diagram
Alzheimer's
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Treatment
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Prevention by exercises, healthy diet, no smoking and low alcohol intake
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Pathophysiology
Defective clearance of beta-amyloid plaques by macrophages relates to altered macrophage gene expression
Neuronal loss is selective- confined to hippocampus, amygdala, subcortical nuclei, temporal neocortex
Accumulation leads to progressive neuronal damage, Neurofibrillary tangles, increased amyloid plaques and ACh loss
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