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Multiple myeloma, MUSKULO-SKELETAL DISORDERS (TUMOURS) - Coggle Diagram
Multiple myeloma
Invistigations
Urine electrophoresis, urinary Bence joins protein
FBC+ blood film, anemia +Rouleux formations
Serum electrophoresis, protein spike
MRI-bone lytic lesion e,g raindrop appearance of skull
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clinical manifestations
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Constipation, fatigue and appetite loss
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Pathophysiology
Multiple myelomacauses cancer cells to accumulate in the bone marrow where they crowd out healthy cells
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Definition
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It is a monoclonal proliferation of plasma cells in the bone marrow resulting to production on monoclonal proteins like immunoglobulins and light chains
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