image

AINES

INHIBE COX-2

INHIBICIÓN DE COX 1, RA EN TD

image

Bloquean la síntesis de PGs al inhibir COX

unión rápida y reversible

image

unión rápida y baja afinidad

reversible, seguida de unión mas lenta

gran afinidad, reversible

image

unión rápida, reversible

modificación reversible

image

Reducen inhibición reversible dependiente de tiempo

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image analgésica

Consecuencia directa del síntesis de PGs

image Antipirética

image

Incremento de síntesis de PGE2.

DERIVADOS DEL PARAAMINOFENOL

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

DERIVADOS DE ÁCIDO PROPIÓNICO

image

image

image

image

image

INHIBIDORES NO SELECTIVOS DEL COX

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

image

DERIVADOS DE INDOL

image

image

DERIVADOS CARBOXILICOS Y PIRROLICOS

image

image

image

image

image

image

image

image

AINES

Hernández Zamora Lizbeth