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HEMATOPOIESIS - Coggle Diagram
HEMATOPOIESIS
3) MYELOID/ MEDULLARY
Adult stage
Bone marrow
= primary site
Red
cellular
Hamatopoietic cells
Yellow
Adipocytes (fats)
starts at 4th to 5th month of fetal dev
(Peak) 24th week of gestation
BM
Adult
Proximal end of bones
tibia
Femur
pelvic area
sternum
vertebra
Mesenchymal cels
Stromal cells:
Endothelial cells
Reticulo-adventicial cells
Myeloid-to-erythroid
= 3:1 or 4:1
Hemoglobins
Hb F
Hg A
= Predominant
Growth factors
Erythropoietin (EPO)
Colony Stimulating Factors:
Granulocytic-CSF
Granulocyte Macrophage CSF
2) HEPATIC
Fetal dev. stage
Fetal liver
Stage 1
Begins at 2nd - 3rd month of fetal dev
Stage 2
(Peak) 6th month
Primary site = LIVER
Stage 3
(decline) 1-2 weeks after birth
Cells:
Developing erythroblast
Granulocyte
Monocye
Megakaryocyte
Hemoglobins:
Hb F
= Predominant
Hg A
1) MESOBLASTIC
Embryonic dev. stage
Yolk sac
Aorta gonad mesonephros (AGM) region
Hematopoietic Stem Cells (HSC)
19th day; Mesoderm to yolk sac
Cells found:
Primitive erythroblast
Angioblast
ANGIOGENESIS - formation of BV
extravascularly (blood vessels)
Hemoglobins
Gower 1
Gower 2
Portland