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Rheumatoid Arthritis Inflammation of the synovial membrane,…

- - - - secrete
        
        IL-2
        
        IFN-gamma
        (both in small quantities)
    - - secrete
        
        IL-17
        --> induces FLS activity
        -->induces RANKL expression
- - - - Secrete (continuously)
        
        IFN-gamma
        
        TNF-alpha
        --> stimulates angiogenesis
        --> impaires barrier function
        --> induces paneth cell necrosis
        
        IL-1
        
        IL-6
        
        IL-17