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Immunity Group 6: T-cells, Cytokines, NK cells, https://cellcartoons…
Immunity Group 6: T-cells, Cytokines, NK cells
Cytokines
Signaling proteins affecting behavior of other cells (immunomodulators) to add or reduce the functions of response
Many types for different responses as cells produce their own cytokines
Lymphokines (B/T Cells)
Monokines (Monocytes)
Interferon (T Cells/Macrophages) have antiviral properties
Chemokines help with chemotaxis
Tumor Necrosis Factor
Lymphotoxin
Activation of macrophages, WBCs, fibroblasts & endothelial cells. Responsible for systemic effects of inflammation like loss of appetite or increased heart rate
Produced by cells of the immune system & play active role in activation of immunity response
Controls infection response & developmental processes during embryogenesis
Natural Killer cells: innate immunity
Develops from bone marrow stem cells
Lymphocytes that destroy foreign cells
Found only in microcirculation, not tissue
Active against viruses and cancer cells
Activity can be compromised such as with HIV infection
T-cells!!!!!
Develops from a hematopoietic stem cell and travels to the thymus, where it is processed into a mature cell
Distinguished from other lymphocytes by the presence of a special receptor called T-cell Receptor (TCR)
Different types of t-cells with different functions:
T-Helper Cell
T-Suppressor Cell
T-cytotoxic cell
T-memory Cell
T- Helper Cell:
increases the functioning of the B Cell, enhancing the antibody response produced by plasma cells.
orrganize and help to "alert" other cells to coordinate the immune system to clear pathogens
T-suppressor cell: carries the CD8 cell receptor and suppresses the functioning of the B-cell
T-cytotoxic cell: also carries the CD8 cell, but is in active surveillance against virally infected cells and neoplastic cells- attacking these cells
T-memory cell: retains a memory of the antigen and reacts by duplicating itself many times over in a process called clonal selection,
all processed antigens are presented to T cells in the context of the major histocompatibility complex (MHC)
https://cellcartoons.net/lymphocytes/
