Please enable JavaScript.
Coggle requires JavaScript to display documents.
Chronic renal failure - Coggle Diagram
Chronic renal failure
Complications
-
Ca/PO4- balance = increase phos, PTH, decrease serum Ca, calcitriol
phosphate binders, calcimimetics
hyperkalemia
restrict diet, avoid NSAIDs
-
Na+ retention, volume overload
Na+ restriction, diuretics
Definition
irreversible, permanent loss of nephrons
-
urea, creatinine not change much over time
-
Biochemical consequences
Endocrine functions
VitD activation
-
Renal osteodystrophy
Pathogenesis: Phos > release FGF-23 > decrease vitD > decrease Ca > increase PTH > bone reabsorption (chew up bone matrix to increase serum calcium)
-
-
Treat
-
dialysis, renal transplant
-
-
-
-
Reabsorption
lose Na+ and water
dehydration, lots of urine
later, cannot excrete fluid = fluid overload
Measure renal function
measuring GFR = a number
-
What: how many ml of plasma can kidneys clear of ideal substance in one minute corrected to body SA?
-
-
-