Please enable JavaScript.
Coggle requires JavaScript to display documents.
The Human Brain and Depression - Coggle Diagram
The Human Brain and Depression
Frontal Lobe
Language
Broca's aphasia
Working memory
multitasking problem
Attention
decreased alertness
Initiation
Aphaty
Inhibition
personal social disintegration
Monitoring
impersistence
Emotion
euphoria, depression, social behavior
Endocranial Shape/ancestral linkage
Modern day humans (e.g.
H. sapiens
)
globular brains and globular endocasts with steep frontal, bulging parietal, and enlarged, rounded cerebellar areas.
Neandertals
anterior-posteriorly elongated endocasts
H. erectus
smallest of the brain sizes
Brain Systems
frontoparietal network
regulation of emotions
default mode network
internal world mental processes/autobiographical memory
dorsal attention network
attention to the outer world
medial temporal lobe network
knowledge acquisition regarding experiences from our past
amygdala
emotional memory
right amygdala
automatic and fast detection of stimuli with emotional charges
left amygdala
detailed analysis of stimuli
Pathogen Host Defense hypothesis: PAThos HOSt Defense = PATHOS-D
depression
Immunology
behavioral responses
Allelic variants that increase risk of depression
located in genes with known immune effects: dopamine and serotonin are pivotal neurotransmitters in mood regulation
increase signaling in inflammatory due to induced cytokines
increase survival in the context of infection
CNS
brain/spinal cord (mesencephalon)
neuronal evolution involved the metazoans
reptilian brain is the most primitive
Hypotheses of brain evolution:
inferential brain hypothesis
changes in structure/function relationships of brain regions
social brain hypothesis
increased sociality is responsible for enhanced cognition
reinterpretation hypothesis
primates gained the ability to detect environmental regularities/ability to infer information
Bulging
Parietal Bulging
orientation, attention, perception of stimuli, sensorimotor transformations underlying planning, visuospatial integration, imagery, self-awareness, working and long-term memory, numerical processing, and tool use
Cerebellar Bulging
motor-related functions and balance spatial processing, working memory, language, social cognition, and affective processing