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γδ T cells - Coggle Diagram

- - - - induction of TNF .IFN
        
        recruit Neu
    - - activate dermal γδ T
        
        memory like behavior
      - shifting from Vγ1+ and Vγ2+ to Vγ4+ T cell subset
        
        clearnece on secondary infection
  - - - cytotoxic potential
        
        cytotoxic mediators
      - antimicrobial peptides
      - against intracellular pathogens
        
        IFN,TNF
    - - FUNCTIONAL PLASTICITY
        
        COexpression IL17.IFN
      - promote dendritic cell
        cross-priming for CD8+ T cells during L. monocytogenes
      - reside and
        persist as long-lived cells
  - - - recruitment of Neu
      - IL17 dependent manner
      - mature granolumas in M.tuburclosis
    - - Vγ9Vδ2 T cells
        
        IL2/7, IFN
        
        recognize
        a phosphoantigen BY M.tuburclosis
        
        durable memory like response, single and selective (HMB-PP-based) immunization of Vγ9Vδ2 T cells was able to elicit fast-acting and durable memory-like responses
  - - - Vδ1+,and Vδ3+ T cell subsets
        
        memory phenotype
        
        IFNγ and TNF production and in
        cytotoxicity, thus limiting virus propagation in vitro
- - - - local inflammation
        
        successful implantation
- - - - secretion of IL33 by stromal cells
        
        local maintenance of
        regulatory T cells,
        
        fat lipolysis
        
        regulates
        thermogenesis
- - - - increasing glial cell production of BDNF
        
        synapticplasticity