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HBB下调 HBG1/2上调 - Coggle Diagram

- - - - diff-peak diff-anonotatino diff-motif diff-TFs
    - - diff gene co-expression
        
        combining analysis
        
        activate HIF pathway
        
        qPCR candidate gene(need HUDEP2 WT and HBB-KO cDNA) ~6 cm dish and HUDEP2 WT and HUDEP2 HBB-KO cells
        
        erythroid differentiation
        
        qPCR erythroid markers
        
        Flow cytometry data (CD71， CD235a)
        
        Heme or Fe
        
        PI3K/Ak- STAT3 pathway
    - - diff gene
    - - diff phosphorylated peptids diff kninase