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Staphylococcus saprophyticus, GROUP 6 2024C SUMAGAYSAY-TIENZO - Coggle…
Staphylococcus saprophyticus
Test Results
Catalase (+)
Coagulase (-)
Nitrite (-)
Resistant w Novobiocin
Habitat/Reservoir
Skin
Periurethral area
Urethral flora
Gastrointestinal tract (main reservoir, part of normal human microflora)
Culture
Pinhead, slightly larger cones
Non-hemolytic
White opaque
50% of strains: Pigmented
Anaerobic
Nonmotile
Non spore-forming
Glucose fermenting
Grow most rapidly at 37C
Forms pigment best at room temperature (no pigment anaerobically or in broth)
Colonies: round, smooth raised and glistening
Pathology
UTI in sexually active young women
Complications in acute pyelonephritis, epididymitis, urethritis and prostatitis
Urothelium: edematous and ulcerated
Cystitis
Morphology
Gram (+)
Cocci
Arranged in clusters/pairs
Colonies: white-yellow, glossy
Treatment
SEVERE UTIS CAUSED BY ORGANISM: Nitrofurantoin 100mg orally 2x/day for 5 days
UNCOMPLICATED CASES: Trimethoprim-sulfamethoxazole (TMP-SMX) 160mg/800mg orally 2x/day for 3 days
Virulence Factors
Urease
Selective adherence to human urothelium
Enzymes
Catalase
Hyaluronidase/Spreading factor
Clumping Factor
Toxins
Hemolysin
TSST-1
Exfoliative Toxins A (heat stable) & B)
Enterotoxins
Antimicrobial Resistance
Resistant w Novobiocin
GROUP 6
2024C
SUMAGAYSAY-TIENZO