Please enable JavaScript.
Coggle requires JavaScript to display documents.
DIGESTION & ABSORPTION Pt.2-Proteins - Coggle Diagram
DIGESTION & ABSORPTION Pt.2-Proteins
Proteins & Amino acids
AA
-Carboxyl & amino group attached to alpha Carbon
20 standard AA , 300 Non-standard
Proteins
-large , built from series of AA linked by peptide bonds
Amino acids
Essential AA
>>Adequate Protein synthesis
Non-essential
>synthesis via interconversion
Interconversion of AA
Protein Digestion
Begins in the stomach
HCL
activates
inactive pepsinogen
to pepsin
Pepsin
digests protein/collagen to
peptones(
lager
) & proteoses(
smaller
)
>>move to small intestines>intestinal mucosa stimulate brushborder enzyme-
enterokinase
which activates the
inactive trypsinogen
to trypsin
Trypsin
activates inactive
chymotrypsinogen to chymotrypsin
& activates
inactive procarboxy to carboxy peptidase
Trypsin/ chrymotrypsinogen/carboxy peptidase digests protein,peptones & proteoses to dipeptides
Dipeptides
in brush order hydrolyzed by depeptidase to AA<absorbed
Protein Transport-Absorption
Active transport of dipeptides & tripeptides via Peptide transporters
Large intact peptides absorbed(antibodies to food proteins)
Some Na+ or Cl- dependent
Sources of Proteins
Dietary Proteins
-80-100mg
Endogenous Proteins
(50-60g)-mucoproteins, digestive enzymes, leaked plasma protein & shed epithelial cells
Protein Turnover
Amino acid pool
:Dietary & endogenous proteins + Protein breakdown
Protein digestion=protein synthesis(balanced)
Important for replacing old & damaged protein
Amino acids
used to produce energy, synthesize glucose or fatty acids & non-protein molecules with nitrogen
NH3, urea,CO2 formed/eliminated after the metabolizing