Nutritional Disorders
(Pediatrics)

Overweight and Obesity

Prenatal factors

high preconceptual weight

maternal smoking

gestational weight gain

high birth weight

Breastfeeding>>>only modestly protective

measurement

BMI

Formula

= weight in kg/(height in meters)

Adults

BMI ≥30

BMI 25-30

obesity

overweight

Children >2 yr old

BMI ≥95th

obesity

BMI 85th - 95th

overweight

Causes

ENVIRONMENTAL CHANGES

GENETICS

Genetic determinants - FTO gene at 16q12

melanocortin-4 receptor (MC4R) deficiency

ENDOCRINE

GH deficiency

Hyperinsulinism

Cushing syndrome

Hypothyroidism

Pseudohypoparathyroidism

Comorbidities

type 2 diabetes, hypertension, hyperlipidemia,
nonalcoholic fatty liver disease (NAFLD)

metabolic syndrome

(central obesity, hypertension, glucose
intolerance, and hyperlipidemia)

increases risk for CV morbidity and mortality

Identification and Evaluation

Exam: growth chart for weight, height, and BMI trajectories

Laboratory Evaluation

fasting plasma glucose, triglycerides, low- density lipoprotein&high-density lipoprotein,cholesterol, and liver function tests

Intervention

Based on behavior change theories

Drinking lower quantities of sugar

Working with a dietitian

Meals should be based on fruits, vegetables, whole grains, lean meat, fish, and poultry.

Pharmacotherapy

children <16 yr old

Orlistat

Bariatric surgery

BMI ≥40

after failing 6 mo of program

Prevention

PREGNANCY

Do not smoke.

Maintain moderate exercise as tolerated.

Normalize body mass index before pregnancy

POSTPARTUM AND INFANCY

BF 4-6 mo,other foods 12 mo

FAMILIES

Eat meals as a family in a fixed place and time.

Do not skip meals, especially breakfast.

SCHOOLS

Education

COMMUNITIES

exercise and safe play facilities

HEALTHCARE PROVIDERS

Explain the biologic and genetic contributions to obesity.

INDUSTRY

Mandate age-appropriate nutrition labeling for products aimed

GOVERNMENT AND REGULATORY AGENCIES

Classify childhood obesity as a legitimate disease.

Undernutrition

factors

Child-caring practices

Access to health and water/ sanitation services

Household food supply

FOOD SECURITY

4 Dimensions

availability

Access

household level

supply of food

Utilization

Stability

Greatest risk in the first 1000 days,from conception to 24 mo of age

Measurement of Undernutrition

Malnutrition

LBW, <2,500 g

2 main causes

Preterm delivery

Fetal growth restriction

Height-for-age

children <2 yr

LOW

reflects socioeconomic disadvantage

Weight-for-height

LOW

HIGH

acute malnutrition.

overweight

Weight-for-age

most commonly used index

mid-upper arm circumference

Body mass index (BMI)

overweight

obesity

thinness

<−2 SD

+1 SD & +2 SD

More +2 SD

Micronutrient deficiencies

public health significance

  • vitamin A, iodine, iron,& zinc.

Vitamin A

Xerophthalmia

Night blindness & Bitot spots

Iodine deficiency

goiter

pregnancy

cretinism

<100 μg/L indicates insufficient intake

Iron-deficiency

anemia

Zinc deficiency

Consequences of Undernutrition

Fetal programming

associated with an increased risk of hypertension, stroke,type 2 diabetes in adults

Economic consequences

Increased costs of healthcare Productivity losses,
Productivity losses from reduced cognitive ability
Increased costs of chronic diseases
Consequences of maternal undernutrition

Interventions

Promotion breastfeeding for 6 mo , and continued breastfeeding for at least 2 yr

Micronutirient supplements

most cost-effective investment

Vitamin A, Iron,Zinc, salt iodization

Zinc

10-20 mg/day for 2 wk

Severe Acute Malnutrition

6-59 mo, a mid-upper arm circumference <115 mm

Reductive Adaptation

Changes lead to

hypoglycemia

hypothermia

fluid overload

excess body sodium,fluid retention,and edema

GI Infection

amino acid imbalances

Treatment

Rehabilitation phase

Stabilization phase

restore wasted tissues

repair cellular function,
correct fluid and electrolyte imbalance
restore homeostasis

REFEEDING SYNDROME

complicate the acute nutritional rehabilitation of undernourished child

HALLMARK

development of severe hypophosphatemia

2 Common mistakes

Focusing on the illness and treat as for a
well-nourished child.

Treating edema with a diuretic

Giving a high-protein diet in the early
phase of treatment.

Community-based Therapeutic
Care

RUTF is usually provided

Steps

Emergency Treatment

Stabilization

Rehabilitation