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GENITAL ULCER SYNDROME+Gen. warts - Coggle Diagram
GENITAL ULCER SYNDROME+Gen. warts
Cause
Herpes simplex virus (HSV-1 and HSV-2)
Treponema pallidum – syphilis
Haemophilus ducreyi - chancroid
Chlamydia trachomatis serogroups L1, L2, L3-- lymphogranuloma venereum (LGV)
Klebsiella (Calymmatobacterium) granulomatis- donovanosis / granuloma inguinale
Clinical features
Painful/painless
Blisters/vescicles in Herpes
Single/multiple
Lymphadenopathy,tender-Herpes , Rubbery-Syphilis,bubous-painful,flanctuant(pus filled)>chancroid/LGV
2ndary Syphilis signs >rush on soles of feet , mucous membranes lesions-chondylomata lata
Treatment
Benzathine penicillin IM (Syphilis)
Acyclovir oral (herpes)
azithromycin oral (chancroid, LGV)-after 7 days
If buboes, aspirate , if fluctuant = azithromycin (chancroid, LGV)
HIV & ULCERS
HIV Susceptibility
↑ activation of HIV susceptible cells
Damage mucosal integrity
HIV shedding
Bleeding during sex
↑ [HIV-1]
Genital Warts
>HP(6,11),↑Prevelance in HIV px , Prev=vaccination,HPV(16,18)>Cervical , genital cancer, resolve simultaneously(other treatment(s.38)