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MED MICRO-Serology - Coggle Diagram
MED MICRO-Serology
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2.Epidemiology
Untreated pregnant women>Fetal loss, still birth , neonatal death, LBW infants, or infected infants :
HIC>>Risky behaviors (gays, transgender , sex worker & HIV+)
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3.Pathogenesis
Venereal syphilis
Infectious-1º & 2º syphilis>moist, mucocutaneous lesions and high loads of spirochetes in blood present
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Host antibodies produced>help with uptake and degradation of spirochetes via phagocytosis>cytokine produced>adaptive immune response
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Congenital
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Infected placenta>large & pale, weigh 1/3 as much as fetus
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Early findings>>stillbirth, neonatal death, desquamating rash, lymphadenopathy etc.