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MED VIROLOGY 2(pt.1) - Coggle Diagram
MED VIROLOGY 2(pt.1)
T cell Haemostasis
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HIV infection>>↑ Death rate of the cells>cells replaced by cell division of mature lymphocytes in the 2ndary lymphoid organs.
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cell death rate exceeds the immune system capacity to replace the lost T cells>>CD4 cell fall> failure
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MALT
HIV infection>damages MALT>breaks barrier>GUT becomes leaky allowing antigens to gain access>>translocation of antigens into systemic circulation
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main site of viral persistence
GUT lymphoid tissue