Pharmaceutical pellets
What is pellets: small free flowing spherical units ranging in size prepared by agglomeration of fine powders called pellets 
Why pellets :
Mechanism of drug release from multiparticulates:
Taste making: micropellets are ideal for products where perfect abatement of taste is required.
Immediate release: Administering drugs in pellet form leads to increased surface area as compared to traditional compressed tablets and capsule.
Sustained release: pellets are being increasingly used in the manufacture of sustained release dosage form of drugs.
Diffusion: on contact with aqueous fluids in the gastrointestinal tract water diffuses into the interior of the particle. Drug dissolution occurs and the drug solutions diffuse across the release coat to the exterior.
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Erosion: some coatings can be designed to erode gradually with time thereby releasing the drug contained within the particle.
Osmosis: In allowing water to enter under the right circumstances an osmotic pressure can be built up within the interior of the particle the drug is forced out of the particle into the exterior through the coating
Advantage of pellets: Improved anesthetic appearance of the product.
- Coating of drug pellets with different polymers to achieve controlled release rate of drugs.
- Potential side effects are minimised without markedly lowering drug bioavailability.
Method of pelletization:
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Agitation
Compaction
Layering
Globulation
Balling
Compression
Extrusion
Poweder
Solution/ suspension
Spray Drying
Spray congealing