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Rheumatoid Arthritis - Coggle Diagram

- - - - higher risk for heart attack
- - - - autoimmune disorder
    - - often the triggering event is unknown
    - - Immune system mistakenly attacks healthy cells
      - Antibodies and antigens create immune complexes within the synovium
        
        immune complexes trigger complement system which creates an exaggerated inflammatory response.
        
        increased vasodilation/capillary permeability that causes the warm swollen and painful joints.
  - - - cartilage cannot get nutrients
      - collagen fills gaps and fibrosis forms
        
        impairment of joint mobility and ankylosis
        
        atrophy