platelet
• Platelets are very small non-nucleated cells with fine granules that derive from fragmentation of megakaryocytic.
• General Characteristics of Platelets
Platelets are the smallest blood cells
• They are cytoplasmic fragments derived from their bone marrow precursor, the megakaryocyte.
• Resting platelets have a smooth disk shape and are 3.6 ± 0.7 µm in diameter. On activation, platelets undergo a shape change, becoming a compact sphere with numerous long dendritic extensions, markedly increasing their surface area.
•In humans, normal platelet counts range from 150,000/µL to 450,000/µL.
•The main function of platelets is to maintain vascular integrity, thereby playing a crucial role in hemostasis.
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