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ARF & RHD - Coggle Diagram
ARF & RHD
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Epidemiology
Age>ARF peaks =5-14 years , RHD: Peaks=20-24yrs
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Definitions
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(RHD) >> accumulated heart valve damage from multiple recurrent ARF episodes involving the mitral and aortic valves.
Diagnosis
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1 major , 2 minor(except chorea & indolent carditis
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Pathogenesis
GAS pharyngeal infection>>activation of the innate immune system >GAS antigen Presentation>T Cells>IgM/G produced>CD4 T cells
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Treatment
NSAIDs, antibiotic therapy and heart
failure management.