Please enable JavaScript.
Coggle requires JavaScript to display documents.
Activity of acetyltransferase toxins involved in Salmonella persister…
Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection
-
-
Conclusion
- Salmonella respond to internalization by primary human macrophages by dramatically increasing the proportion of persisters.
- Chromosomal class II TA modules were shown to contribute to persister formation.
The single aa change E29K dramatically increases activity of TacT2
--> TacT2SEn compensates for the loss of ParE and RelE1
- TacT2 and TacT3 represent new acetyltransferase toxins
- Also, the three different toxins have specificity for their substrate
