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Gut microbiome - Coggle Diagram
Gut microbiome
dietary fiber
SCFA produced from digestion of fiber: acetate, propionate, butyrate
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3. inhbits IL-18, an inflammatory molecule, and ultimately inhibits carcinogenesis and inflammation
acts on PYY reduces intestinal transit time, making people feel full for longer, and stimulates leptin secretion from adipose tissue
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brain
peripheral serotonin
2. Gut microbes produce serotonin, which may affect signaling in the brain
serotonin producing bacteria: Lactococcus lactis, Lactobacillus plantarum, streptococcuc thermophilus, E. coli, Morganelli morganii, Klebsiella pneumoniae, Hafnia alei
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immune system
intestinal microbiome can initiate production of cytokines by immune cells that can impact neurophysiology
bacterial molecules
metablites produced by the microbes can alter the activity of cells in the blood-brain barrier, for example butyrate
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Colon
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SCFA also impact IL-18, an inflammatory molecule, and ultimately inhibits carcinogenesis and inflammation
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high energy intake
inhibits the enzyme HDAC, resulting in inflammation and carcinogenesis
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