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MED MICRO 2 - Coggle Diagram
MED MICRO 2
LAB DIAGNOSIS
Culture
Adv>gold standard, isolate available
Disava>slow , labour intensive, expensive, bioharzadous
Solid=LJ edium , Liquid, Bactet MGIT
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Specimen :
Expectorated, induced , nasogastric aspartate(gastrc washings)
Molecular
Gene Xpert
Adv:more sensitive than microscopy,<2 hrs, closed system,
Disadv: Cost , centralization vs decentralization
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Immunological
Mantoux(Tuberculin Skin test)>latent TB, Size of reaction, intradermal, after 3 days, compared to reference
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Antigen
Detects Mtb cell wall , easy ,less hazardous, people with HIV, RAPID, No susceptibility test results
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HISTORY
PT>Productive vs not, cough more than 2 wks
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Onset>fever, night sweats, weight loss
EXAM
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SOB, Cogh productivity , Ausculutations unremarkable
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CLINICAL FEATURES
ACTIVE>>
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Reactivation(2ndary)>>UL Cavitary , bacilli in apices(high ventilation)>>reactivate causing fibrosis & cavities
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Radio Features(PT)>>
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CAVITATION in upper lobes, nodular infiltrates
EP
Commonly>>lymph node, pleural, meningitis,peritoneal
DIAGNOSIS
Biopsy/fluid>>istology, microscopy,culture,mol. tests
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