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PHYSIOLOGY 3-PERFUSION REGULATION - Coggle Diagram
PHYSIOLOGY 3-PERFUSION REGULATION
Pulmonary Circulation
Lung vessels>>hold Cardiac output generated by right(lung vessels have higher capacitance**>Low pressure)
Lung vessels are compliant(Capacitance)>>need to hold the CO
generated by Right Heart>>generates 25/0 pressure to go over lung circulation>>result in MAP of 12 mmHg>
Pulmonaery Artey Pressure
High Pressure>>Pulmonary Hypertension>>affects Gaseous exchange
measured by PA catheter>canula into pulmonary artery>thread catheter from big vein>RA>RV>Out to lungs
Effects of Gravity
Apex independent>low perfusion>low PAP
Base dependent>>high perfusion>High PAP>>likely to form pulmonary oedema because of greater hydrostatic pressure in circulation>>
(upright
subject)> crackles in bases of lungs ,
(supine)
area with great diffusion is distributed across greater area of lung>>more breathless(work up at night>>paroxysmal nocturnal dyspnea>want to be upright>>minimize the area with oedema)
RESPIRATION PUMP
During expiration>>blood
squeezed
out "pulmonary squeeze" >>temporary increase in peripheral blood pressure
Systemic blood Pressure changes during respiration(Low in Insp. and high in exp.)>>>PULSUS PARADOXUS
During inspiration>>creates vacuum>promotes venous return>blood pulls within lung's capacitance vessels
Exaggeration of pulsus paradoxus>>pathologic
OTHER FACTORS
Parasympathetic>Vagul dilator
Local factors:acidosis , hypoxia(vasoconstriction)
Sympathetic(adregernic)