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HISTOLOGY PART 2 - Coggle Diagram
HISTOLOGY PART 2
LYMPH NODE STRUCTURE:Slide12)
Lymphatic flow
>incoming(afferent) lymphatics>>drain to subcapsular sinus surrounding the lymph node(btwn capsule and lymphoid tissues inside lymph node>>filters via cortical regions>>medulla>>efferent lymphatics)
B& T lymphocytes come via bloodstream
Dense fibrous connective tissue capsule & and trabecula
Dense network of Capillaries>>in the cortex>>where lymphocytes are able to act with antigens........
Nodules
in cortex >>surrounded by dense network of blood capillaries>>allow interacion of antigens and blood born immune cells
Network around cortical nodules>>lymphoid follicles>>
LYMPH NODES FUNCTONS
INTERACTION>>Uptake of antigen via APC
AGGREGATION
FILTRATION>>Removal
PROLIFERATION
ACTIVATION
LYMPOID FOLLICLES(slide 14)
2ndary Activated follicles(stimulated by antigens)-proliferation of lymphocytes>>
germinal centers(pale)
>>surrounded by mantle/corona(crown-surrounds)
Primary(non-activated)
Interstitial compartment
Different follicles>>each follicle houses B cells that are specific to certain antigens
PALATINE TONSILS
exposeed to body's surfaces>>stratified squamous epithelial lining
Screens what we ingest>has lymphoid follices
PROTECTION OF RESP. AIRWAYS
ACQUIRED
LAMINA PROPRIA
>>Aggregation of lymphocytes, macrophages, activated of neutrophils, antibodies production
LYMPHOID NODES/TONSILS
>>Site of specific immune responses against antigen>in strategic positions>to help with 1st line of defence>>Antigen presentation>>destruction of antigen , production of antibodies
INNATE
Mucosal Surface
: mucociliary escalator, antimicrobial enzymes(serous fluid), antiproteases(Clara &serous fluid), SF-A, SF-D